PSG1 Antibody

Datasheet
Code CSB-PA018849ESR1HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA018849ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA018849ESR1HU at dilution of 1:100

  • Immunoprecipitating PSG1 in A549 whole cell lysate
    Lane 1: Rabbit control IgG instead of CSB-PA018849ESR1HU in A549 whole cell lysate. For western blotting, a HRP-conjµgated Protein G antibody was used as the secondary antibody (1/2000)
    Lane 2: CSB-PA018849ESR1HU (8µg) + A549 whole cell lysate (500µg)
    Lane 3: A549 whole cell lysate (10µg)

Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) PSG1 Polyclonal antibody
Uniprot No. P11464
Target Names PSG1
Alternative Names B1G1 antibody; Carcinoembryonic antigen SG8 antibody; CD66 antigen-like family member F antibody; CD66f antibody; CD66f antigen antibody; CEA antibody; DHFRP2 antibody; Fetal liver non-specific cross-reactive antigen 1/2 antibody; FL-NCA-1/2 antibody; PBG 1 antibody; PBG1 antibody; Pregnancy specific B 1 glycoprotein antibody; Pregnancy specific beta 1 glycoprotein 1 antibody; Pregnancy specific beta 1 glycoprotein 2 antibody; Pregnancy specific beta 1 glycoprotein 7 antibody; Pregnancy specific beta 1 glycoprotein 8 antibody; Pregnancy specific beta 1 glycoprotein antibody; Pregnancy specific beta 1 glycoprotein C/D antibody; Pregnancy-specific beta-1 glycoprotein C/D antibody; Pregnancy-specific beta-1-glycoprotein 1 antibody; Pregnancy-specific glycoprotein 1 antibody; PS beta C/D antibody; PS-beta-C/D antibody; PS-beta-G-1 antibody; PSBG 1 antibody; PSBG 2 antibody; PSBG-1 antibody; PSBG1 antibody; PSBG2 antibody; PSG 1 antibody; PSG 2 antibody; PSG 8 antibody; PSG 95 antibody; PSG IIA d antibody; PSG1 antibody; PSG1_HUMAN antibody; PSG2 antibody; PSG8 antibody; PSG95 antibody; PSGGA antibody; PSGGB antibody; PSGIIA a antibody; PSGIIA antibody; PSGIIA b antibody; PSGIIA c antibody; SP 1 antibody; SP1 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Pregnancy-specific beta-1-glycoprotein 1 protein (180-419AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, IHC, IP
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IP 1:200-1:2000
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunoprecipitation (IP) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Gene References into Functions
  1. Inhibiting PSG1 can effectively reduce chemoresistance via a transforming growth factor-beta (TGF-beta)-related pathway in ER-negative breast cancer cells. PMID: 27653744
  2. PSG stimulated IDO activity under the conditions of induction of the monocytes by interferon-gamma. PMID: 27595833
  3. Under conditions of directed induction of phenotypic changes in CD4(+) lymphocytes to regulatory T cells (Treg), pregnancy-specific at high concentrations (10 and 100 mug/mL) increased FOXP3 expression. The evaluation of the spontaneous expression level of FOXP3 mRNA showed that pregnancy-specific beta1-glycoprotein (1 and 100 mug/mL) stimulated the expression of this factor in mononuclear cells and isolated CD4(+) lym... PMID: 27817017
  4. results identify a non-placental site of PSG expression in the gut and associated tumors, with implications for determining whether PSGs have a role in tumor progression, and utility as tumor biomarkers. PMID: 26926266
  5. the presence of GAGs on the surface of endothelial cells was required for the ability of PSG1 to induce tube formation PMID: 21193412
  6. The aspartic acid at position 95 is not required for PSG1 activity but the amino acids implicated in the formation of a salt bridge within the N-domain are essential. PMID: 20335639
  7. first trimester maternal serum marker of small-for-gestational age and preterm delivery PMID: 19911417
  8. Human PSG1a induces alternative activation in human & mouse monocytes & suppresses the accessory-cell-dependent T-cell proliferation. PSG1a contributes to immunomodulation during pregnancy, with opposite effects on maternal innate & adaptative systems. PMID: 12223519
  9. The differential expression of HLA-E and PSG1 in the sperm of fertile and infertile men is discussed. PMID: 18987160

Show More

Hide All

Subcellular Location Secreted
Protein Families Immunoglobulin superfamily, CEA family
Database Links

HGNC: 9514

OMIM: 176390

KEGG: hsa:5669

STRING: 9606.ENSP00000244296

UniGene: Hs.709192

Most popular with customers