PSG1 Antibody

Code CSB-PA005229
Size US$100
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  • Western Blot analysis of K562 cells using PSG1 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
PSG1
Alternative Names
B1G1 antibody; Carcinoembryonic antigen SG8 antibody; CD66 antigen-like family member F antibody; CD66f antibody; CD66f antigen antibody; CEA antibody; DHFRP2 antibody; Fetal liver non-specific cross-reactive antigen 1/2 antibody; FL-NCA-1/2 antibody; PBG 1 antibody; PBG1 antibody; Pregnancy specific B 1 glycoprotein antibody; Pregnancy specific beta 1 glycoprotein 1 antibody; Pregnancy specific beta 1 glycoprotein 2 antibody; Pregnancy specific beta 1 glycoprotein 7 antibody; Pregnancy specific beta 1 glycoprotein 8 antibody; Pregnancy specific beta 1 glycoprotein antibody; Pregnancy specific beta 1 glycoprotein C/D antibody; Pregnancy-specific beta-1 glycoprotein C/D antibody; Pregnancy-specific beta-1-glycoprotein 1 antibody; Pregnancy-specific glycoprotein 1 antibody; PS beta C/D antibody; PS-beta-C/D antibody; PS-beta-G-1 antibody; PSBG 1 antibody; PSBG 2 antibody; PSBG-1 antibody; PSBG1 antibody; PSBG2 antibody; PSG 1 antibody; PSG 2 antibody; PSG 8 antibody; PSG 95 antibody; PSG IIA d antibody; PSG1 antibody; PSG1_HUMAN antibody; PSG2 antibody; PSG8 antibody; PSG95 antibody; PSGGA antibody; PSGGB antibody; PSGIIA a antibody; PSGIIA antibody; PSGIIA b antibody; PSGIIA c antibody; SP 1 antibody; SP1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human PSG1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Inhibiting PSG1 can effectively reduce chemoresistance via a transforming growth factor-beta (TGF-beta)-related pathway in ER-negative breast cancer cells. PMID: 27653744
  2. PSG stimulated IDO activity under the conditions of induction of the monocytes by interferon-gamma. PMID: 27595833
  3. Under conditions of directed induction of phenotypic changes in CD4(+) lymphocytes to regulatory T cells (Treg), pregnancy-specific at high concentrations (10 and 100 mug/mL) increased FOXP3 expression. The evaluation of the spontaneous expression level of FOXP3 mRNA showed that pregnancy-specific beta1-glycoprotein (1 and 100 mug/mL) stimulated the expression of this factor in mononuclear cells and isolated CD4(+) lym... PMID: 27817017
  4. results identify a non-placental site of PSG expression in the gut and associated tumors, with implications for determining whether PSGs have a role in tumor progression, and utility as tumor biomarkers. PMID: 26926266
  5. the presence of GAGs on the surface of endothelial cells was required for the ability of PSG1 to induce tube formation PMID: 21193412
  6. The aspartic acid at position 95 is not required for PSG1 activity but the amino acids implicated in the formation of a salt bridge within the N-domain are essential. PMID: 20335639
  7. first trimester maternal serum marker of small-for-gestational age and preterm delivery PMID: 19911417
  8. Human PSG1a induces alternative activation in human & mouse monocytes & suppresses the accessory-cell-dependent T-cell proliferation. PSG1a contributes to immunomodulation during pregnancy, with opposite effects on maternal innate & adaptative systems. PMID: 12223519
  9. The differential expression of HLA-E and PSG1 in the sperm of fertile and infertile men is discussed. PMID: 18987160

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Subcellular Location
Secreted.
Protein Families
Immunoglobulin superfamily, CEA family
Database Links

HGNC: 9514

OMIM: 176390

KEGG: hsa:5669

STRING: 9606.ENSP00000244296

UniGene: Hs.709192

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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