RFX5 Antibody

1. RFX5 acts as a direct positive transcriptional regulator of TPP1 in hepatocellular carcinoma. PMID: 27840983
2. Data show arginine methyltransferase PRMT6 methylates the AT-hook motif of regulatory factor RFX5 and downregulates HLA-DQ expression. PMID: 23911394
3. these data have identified as novel pathway whereby SIRT1 maintains COL1A2 synthesis in SMCs by modulating RFX5 activity. PMID: 23079621
4. RFXAP(C) consists of two alpha-helices that form a V-shaped structure that packs within the RFX5(N)(2) staple. PMID: 20732328
5. interaction at COL1A2 start site and transcription repression PMID: 11986307
6. The mutation for the fifth Bbare lymphocyte syndrome complementation group was found in RFX5 and was mapped to one of the arginines in a DNA-binding surface of this protein. Its wild-type counterpart restored function. PMID: 12368908
7. RFX5 binds to the collagen transcription start site and represses collagen gene expression PMID: 12968017
8. The identification of nuclear import and export sites on RFX molecules provides potential targets to modulate MHC class II expression. PMID: 15210800
9. RFXAP and RFXB have roles in relieving autoinhibition of RFX5 PMID: 18723135
10. TSA treatment enhances the association of CIITA with the transcription factor RFX5, which ameliorates the down-regulation of CIITA recruitment to target promoters by HDAC2. PMID: 19041327

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HGNC: 9986

OMIM: 209920

KEGG: hsa:5993

STRING: 9606.ENSP00000290524

UniGene: Hs.632472