RING1 Antibody

1. High RING1 expression is associated with hepatocellular carcinoma. PMID: 29187402
2. Mutation of RING1 is associated with neurodevelopmental abnormalities PMID: 29386386
3. study identified novel interactions between CD147 and RING1, recovered CD147 nuclear envelope distribution in melanoma cells, and suggested a new mechanism underlying how cytoplasmic CD147 promotes melanoma development PMID: 28832687
4. The release of epigenetic repression by nitrosylation of RING1A is critical for effective cell transdifferentiation. PMID: 27623813
5. The polycomb complex proteins BMI1 and RING1A regulate the ubiquitination of chromatin associated proteins bound to promoters. PMID: 26578590
6. On the basis of these results, we proposed that the expression of Ring1 protein may be a novel indicator of hepatocellular carcinoma prognosis. PMID: 26141041
7. High RING1 expression is associated with non-small cell lung cancer. PMID: 24414991
8. HSCARG interacts with RING1 and inhibits RING1 ubiquitination. PMID: 24711370
9. Overexpression of the EZH2, RING1, and BMI1 genes is common in MDS and indicate poor prognosis. The products of these genes might participate in epigenetic regulation of Myelodysplastic syndromes. PMID: 21125401
10. USP7 was identified as a deubiquitinating enzyme that regulates the ubiquitination state of RING1B. PMID: 20800574
11. PcG protein RING1 is associated with adverse pathological features and clinical PSA recurrence in prostate cancer. PMID: 17134822
12. Studies in mammalian cells have found a multiplicity of protein complexes containing Ring1A and Ring1B, suggesting an expanded regulatory role for Ring1A, Ring1B proteins in the epigenetic regulation of gene expression. PMID: 19412891

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HGNC: 10018

OMIM: 602045

KEGG: hsa:6015

STRING: 9606.ENSP00000363787

UniGene: Hs.631989