RPL34 Antibody

Code CSB-PA299301
Size US$297
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  • Western blot analysis of extracts from HepG2 cells, HeLa cells and HUVEC cells, using RPL34 antibody.
  • Immunofluorescence analysis of HuvEc cells, using RPL34 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RPL34 Polyclonal antibody
Uniprot No.
Target Names
RPL34
Alternative Names
60S ribosomal protein L34 antibody; L34 antibody; MGC111005 antibody; Ribosomal protein L34 antibody; RL34_HUMAN antibody; rpl34 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from internal of Human RPL34.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB,IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
IF 1:100-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the large ribosomal subunit.
Gene References into Functions
  1. The RPL34 gene was highly expressed in OSCC, while silencing RPL34 could block cell proliferation and metastasis, but promote cell apoptosis, suggesting the RPL34 gene to be a new promising clinical target for OSCC therapy. PMID: 28697409
  2. RPL34 plays an important role in the proliferation of osteosarcoma cells. PMID: 27883047
  3. RPL34 functions as an oncogene that modulates the proliferation and metastasis of esophageal cancer cells in part through the inactivation of the PI3K/Akt signaling pathway PMID: 28109079
  4. this study shows that ribosomal protein L34 promotes the proliferation, invasion and metastasis of pancreatic cancer cells PMID: 27845896
  5. RPL34 plays a critical role in cell proliferation, cell cycle distribution and apoptosis of human malignant gastric cells. PMID: 26323242
  6. over-expressed RPL34 may promote malignant proliferation of NSCLC cells, thus playing an important role in development and progress of NSCLC PMID: 26526135

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Subcellular Location
Cytoplasm, cytosol. Cytoplasm. Endoplasmic reticulum.
Protein Families
Eukaryotic ribosomal protein eL34 family
Database Links

HGNC: 10340

OMIM: 616862

KEGG: hsa:6164

STRING: 9606.ENSP00000378160

UniGene: Hs.438227

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