RPLP0 Antibody

1. The presence of uL10 on the ribosomes is affected in stressed cells, thus it might be considered as a regulatory element responding to environmental fluctuations. PMID: 28986221
2. absence of RPLP0, RPLP1, or RPLP2 resulted in reactive oxygen species (ROS) accumulation and MAPK1/ERK2 signaling pathway activation. PMID: 26176264
3. This study shows a spontaneous humoral immune response to ribosomal P0 protein in colorectal cancer patients. PMID: 25889931
4. Down-regulation of RPLP0 resulted in G1 arrest of gastric cancer cells PMID: 25433997
5. the immune response mediated by serum anti-RPLP0 and anti-galectin 3 antibodies plays a key role in the pathogenesis of SLE skin lesions. These findings provide new insights into the mechanism of SLE-related organ disorders. PMID: 25307291
6. Evaluated autoantibodies against native ribosomal P complex and recombinant ribosomal P proteins (anti-Rib-P0, anti-Rib-P1, anti-Rib-P2) for prevalence, diagnostic relevance&clinical associations in a Chinese cohort with systemic lupus erythematosus. PMID: 23400861
7. P proteins are up-regulated in a considerable number of patients with the most common types of cancer. PMID: 21040949
8. The P0 protein was found in the cytoplasm, as well as in the nucleus; however, the nucleoli were excluded. This protein was scattered around the nuclei, and the distribution might reflect association with the so-called nuclear bodies PMID: 12479870
9. Recombinant fusion protein GST.P0 expressed in insect cells, but not the protein obtained in Escherichia coli, had the ability to form a complex with P1 and P2 proteins. PMID: 15336536
10. P0 overexpression may cause tumorigenesis in breast and liver tissues at least in part by inhibiting GCIP-mediated tumor suppression. PMID: 17621266

Show More

Hide All

HGNC: 10371

OMIM: 180510

KEGG: hsa:6175

STRING: 9606.ENSP00000339027

UniGene: Hs.546285