RPLP0 Antibody

Code CSB-PA153990
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA153990(RPLP0 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA153990(RPLP0 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Hela cells, 293T cells, A431 cells, Jurkat cells, Primary antibody: CSB-PA153990(RPLP0 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details

Uniprot No.
Target Names
RPLP0
Alternative Names
36B4 antibody; 60S acidic ribosomal protein P0 antibody; 60S ribosomal protein L10E antibody; Acidic ribosomal phosphoprotein P0 antibody; Arbp antibody; L10E antibody; LP0 antibody; MGC107165 antibody; MGC107166 antibody; MGC111226 antibody; MGC88175 antibody; OTTMUSP00000015585 antibody; P0 antibody; PRLP0 antibody; Ribosomal phosphoprotein; acidic; P0 antibody; Ribosomal protein P0 antibody; Ribosomal protein; large; P0 antibody; RLA0_HUMAN antibody; rplP0 antibody; RPP0 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Fusion protein of Human RPLP0
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
Gene References into Functions
  1. The presence of uL10 on the ribosomes is affected in stressed cells, thus it might be considered as a regulatory element responding to environmental fluctuations. PMID: 28986221
  2. absence of RPLP0, RPLP1, or RPLP2 resulted in reactive oxygen species (ROS) accumulation and MAPK1/ERK2 signaling pathway activation. PMID: 26176264
  3. This study shows a spontaneous humoral immune response to ribosomal P0 protein in colorectal cancer patients. PMID: 25889931
  4. Down-regulation of RPLP0 resulted in G1 arrest of gastric cancer cells PMID: 25433997
  5. the immune response mediated by serum anti-RPLP0 and anti-galectin 3 antibodies plays a key role in the pathogenesis of SLE skin lesions. These findings provide new insights into the mechanism of SLE-related organ disorders. PMID: 25307291
  6. Evaluated autoantibodies against native ribosomal P complex and recombinant ribosomal P proteins (anti-Rib-P0, anti-Rib-P1, anti-Rib-P2) for prevalence, diagnostic relevance&clinical associations in a Chinese cohort with systemic lupus erythematosus. PMID: 23400861
  7. P proteins are up-regulated in a considerable number of patients with the most common types of cancer. PMID: 21040949
  8. The P0 protein was found in the cytoplasm, as well as in the nucleus; however, the nucleoli were excluded. This protein was scattered around the nuclei, and the distribution might reflect association with the so-called nuclear bodies PMID: 12479870
  9. Recombinant fusion protein GST.P0 expressed in insect cells, but not the protein obtained in Escherichia coli, had the ability to form a complex with P1 and P2 proteins. PMID: 15336536
  10. P0 overexpression may cause tumorigenesis in breast and liver tissues at least in part by inhibiting GCIP-mediated tumor suppression. PMID: 17621266

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Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Universal ribosomal protein uL10 family
Database Links

HGNC: 10371

OMIM: 180510

KEGG: hsa:6175

STRING: 9606.ENSP00000339027

UniGene: Hs.546285

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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