SEC61G Antibody

Datasheet

Code	CSB-PA03509A0Rb
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA03509A0Rb at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SEC61G Polyclonal antibody

Uniprot No.

P60059

Target Names

SEC61G

Alternative Names

SEC61G; Protein transport protein Sec61 subunit gamma

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Protein transport protein Sec61 subunit gamma protein (1-32AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SEC61G Antibody (Product code: CSB-PA03509A0Rb) is Non-conjugated. For SEC61G Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA03509B0Rb	SEC61G Antibody, HRP conjugated	ELISA
FITC	CSB-PA03509C0Rb	SEC61G Antibody, FITC conjugated
Biotin	CSB-PA03509D0Rb	SEC61G Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER). Component of a ribosome-associated ER translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER.

Gene References into Functions

Sequencing of childhood ependymoma samples indicate Sec61 gamma subunit protein (SEC61G)-epidermal growth factor receptor (EGFR) chimeric mRNAs in one infratentorial ependymoma , arguing that this fusion occurs in a small proportion of these tumors. PMID: 29092923
Cotransin, a substrate-selective Sec61 inhibitor, traps nascent transmembrane domains in the cytosolic vestibule, permitting detailed interrogation of an early pre-integration intermediate. PMID: 24497544

Subcellular Location

Endoplasmic reticulum membrane; Single-pass membrane protein.

Protein Families

SecE/SEC61-gamma family

Database Links

HGNC: 18277

OMIM: 609215

KEGG: hsa:23480

STRING: 9606.ENSP00000341538

UniGene: Hs.488282

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Protein processing in endoplasmic reticulum

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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