SECTM1 Antibody

Code CSB-PA819898LA01HU
Size US$299
Image
  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA819898LA01HU at dilution of 1:100

  • Immunofluorescent analysis of PC-3 cells cells using CSB-PA819898LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) SECTM1 Polyclonal antibody
Uniprot No. Q8WVN6
Target Names SECTM1
Alternative Names
SECTM1 antibody; K12 antibody; Secreted and transmembrane protein 1 antibody; Protein K-12 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Secreted and transmembrane protein 1 protein (29-145AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated

The SECTM1 Antibody (Product code: CSB-PA819898LA01HU) is Non-conjugated. For SECTM1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA819898LB01HU SECTM1 Antibody, HRP conjugated ELISA
FITC CSB-PA819898LC01HU SECTM1 Antibody, FITC conjugated
Biotin CSB-PA819898LD01HU SECTM1 Antibody, Biotin conjugated ELISA
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in thymocyte signaling.
Gene References into Functions
  1. CD7 is present on monocytes and tumor macrophages and its ligand, SECTM1, is frequently expressed in corresponding melanoma tissues PMID: 24157461
  2. SECTM1 secreted from bone marrow stromal cells may interact with CD7 to influence GM-CSF expression in leukemic cells. PMID: 24211252
  3. level of SECTM1 expression is likely to be a key factor in innate immune responses and in the immune tolerance of cancerous cells PMID: 21749909
Subcellular Location Cell membrane; Single-pass type I membrane protein. Secreted.
Protein Families SECTM family
Tissue Specificity Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic
Database Links

HGNC: 10707

OMIM: 602602

KEGG: hsa:6398

STRING: 9606.ENSP00000269389

UniGene: Hs.558009

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