SECTM1

SECTM1 (Secreted and Transmembrane 1) is a transmembrane protein typically expressed on the cell membrane. It comprises an extracellular domain, a transmembrane domain, and an intracellular domain. It plays a role in various biological processes, including immune regulation, tumor growth, and neurological function. Its specific function depends on its expression in different cell types and environments. Some studies suggest that SECTM1 may play a role in immune regulation, affecting the activation and function of T cells. Additionally, SECTM1 is associated with the development of certain types of tumors and may be involved in tumor immune evasion. In the nervous system, SECTM1 may be involved in synaptic transmission and neuronal function.

Popular Product

Recombinant Human Secreted and transmembrane protein 1(SECTM1),partial (Active) CSB-MP819898HU

Validated Data

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized CD7 (CSB-MP004953HU) at 5 μg/ml can bind human SECTM1, the EC₅₀ is 1.811-3.372 ng/ml.

LSPR

Activity: Human CD7 protein hFc and Myc tag (CSB-MP004953HU) captured on COOH chip can bind Human SECTM1 protein hFc tag (CSB-MP819898HU) with an affinity constant of 1.84 nM as detected by LSPR Assay.