SLC27A5 Antibody

Datasheet

Code	CSB-PA006751
Size	US$119
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Image	Western Blot analysis of Hela cells using ACSVL6 Polyclonal Antibody
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9Y2P5

Target Names

SLC27A5

Alternative Names

ACSB antibody; ACSVL6 antibody; BA CoA ligase antibody; BA-CoA ligase antibody; BACS antibody; BAL antibody; Bile acid CoA ligase antibody; Bile acid-CoA ligase antibody; Bile acyl CoA synthetase antibody; Bile acyl-CoA synthetase antibody; Cholate CoA ligase antibody; Cholate--CoA ligase antibody; FACVL3 antibody; FATP 5 antibody; FATP-5 antibody; FATP5 antibody; Fatty acid Coenzyme A ligase very long chain 3 antibody; Fatty acid transport protein 5 antibody; Fatty-acid-coenzyme A ligase antibody; FLJ22987 antibody; S27A5_HUMAN antibody; Slc27a5 antibody; Solute carrier family 27 (fatty acid transporter) member 5 antibody; Solute carrier family 27 member 5 antibody; Very long chain acyl CoA synthetase homolog 2 antibody; Very long chain acyl CoA synthetase related protein antibody; very long-chain 3 antibody; Very long-chain acyl-CoA synthetase homolog 2 antibody; Very long-chain acyl-CoA synthetase-related protein antibody; VLACS related antibody; VLACS-related antibody; VLACSR antibody; VLCS H2 antibody; VLCS-H2 antibody; VLCSH2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human ACSVL6.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, IF, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
IF	1:200-1:1000
ELISA	1:40000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Acyl-CoA synthetase that catalyzes the activation of bile acids via formation of bile acid CoA thioesters which is necessary for their subsequent conjugation with glycine or taurine. Both primary bile acids (cholic acid and chenodeoxycholic acid) and secondary bile acids (deoxycholic acid and lithocholic acid) are the principal substrates. Also exhibits acyl CoA synthetase activity that activates very long-chain fatty acids (VLCFAs) by catalyzing the formation of fatty acyl-CoA. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Exhibits long-chain fatty acids (LCFA) transport activity. Plays an important role in hepatic fatty acid uptake and bile acid reconjugation and recycling but not in de novo synthesis of bile acids.

Gene References into Functions

Based on a study of 10 pediatric patients, genetic defects that disrupt bile acid amidation cause fat-soluble vitamin deficiency and growth failure, indicating the importance of bile acid conjugation in lipid absorption. PMID: 23415802
Bile acid-CoA ligase deficiency is a new inborn error of bile acid metabolism [case report] PMID: 22089923
A promoter polymorphism in the FATP5 is associated with the metabolic syndrome and steatosis. PMID: 20945272

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome. Cell membrane; Multi-pass membrane protein.

Protein Families

ATP-dependent AMP-binding enzyme family

Tissue Specificity

Predominantly expressed in liver.

Database Links

HGNC: 10999

OMIM: 603314

KEGG: hsa:10998

STRING: 9606.ENSP00000263093

UniGene: Hs.292177

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

PPAR signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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