SNX10 Antibody, Biotin conjugated

Datasheet
Code CSB-PA896538LD01HU
Size US$299
Uniprot No. Q9Y5X0
Immunogen Recombinant Human Sorting nexin-10 protein (124-201AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Probable phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes. Plays a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. Required for the localization to the cilium of V-ATPase subunit ATP6V1D and ATP6V0D1, and RAB8A. Involved in osteoclast differentiation and therefore bone resorption.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Sorting nexin-10, SNX10
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Signal Transduction
Target Names SNX10
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Probable phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes. Plays a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. Required for the localization to the cilium of V-ATPase subunit ATP6V1D and ATP6V0D1, and RAB8A. Involved in osteoclast differentiation and therefore bone resorption.
Involvement in disease Osteopetrosis, autosomal recessive 8 (OPTB8)
Subcellular Location Cytoplasm, Endosome membrane, Peripheral membrane protein, Cytoplasmic side, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Protein Families Sorting nexin family
Database Links

HGNC: 14974

OMIM: 614780

KEGG: hsa:29887

STRING: 9606.ENSP00000343709

UniGene: Hs.741316

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