STAT5B Antibody, Biotin conjugated

Datasheet
Code CSB-PA022815LD01HU
Size US$299
Uniprot No. P51692
Protocols ELISA Protocol
Immunogen Recombinant Human Signal transducer and activator of transcription 5B protein (1-787AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Signal transducer and activator of transcription 5B, STAT5B
Immunogen Species Homo sapiens (Human)
Research Area Signal Transduction
Target Names STAT5B
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Carries out a dual function
Involvement in disease Growth hormone insensitivity with immunodeficiency (GHII)
Subcellular Location Cytoplasm, Nucleus
Protein Families Transcription factor STAT family
Database Links

HGNC: 11367

OMIM: 245590

KEGG: hsa:6777

STRING: 9606.ENSP00000293328

UniGene: Hs.595276

Pathway Chemokine signaling pathway
ErbB signaling pathway
Jak-STAT signaling pathway
Necroptosis
Th1 and Th2 cell differentiation
Th17 cell differentiation
AGE-RAGE signaling pathway in diabetic complications

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