TARS Antibody

Code CSB-PA023131ESR2HU
Size US$166
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  • Western blot
    All lanes: TARS antibody at 4.85µg/ml
    Lane 1: A549 whole cell lysate
    Lane 2: Hela whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 84, 87 kDa
    Observed band size: 84 kDa

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA023131ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA023131ESR2HU at dilution of 1:100

  • Immunoprecipitating TARS in A549 whole cell lysate
    Lane 1: Rabbit control IgG instead of CSB-PA023131ESR2HU in A549 whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
    Lane 2: CSB-PA023131ESR2HU (8µg) + A549 whole cell lysate (500µg)
    Lane 3: A549 whole cell lysate (10µg)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TARS Polyclonal antibody
Uniprot No.
Target Names
TARS
Alternative Names
cytoplasmic antibody; MGC9344 antibody; SYTC_HUMAN antibody; TARS antibody; Threonine tRNA ligase 1 antibody; Threonine tRNA ligase 1; cytoplasmic antibody; Threonine--tRNA ligase antibody; Threonyl tRNA synthetase antibody; Threonyl tRNA synthetase; cytoplasmic antibody; Threonyl-tRNA synthetase antibody; ThrRS antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Threonine--tRNA ligase, cytoplasmic protein (1-230AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC, IP
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
IP 1:200-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage.
Gene References into Functions
  1. Results show that TARS expression is increased in epithelial ovarian cancer. PMID: 25163878
  2. Our series mainly underscores that interstitial lung disease is frequent in anti-PL7(tars antibody)patients, leading to high morbidity. PMID: 23375620
  3. A previously undiscovered function for TARS as an angiogenic, pro-migratory extracellular signaling molecule. PMID: 23425968
Subcellular Location
Cytoplasm.
Protein Families
Class-II aminoacyl-tRNA synthetase family
Database Links

HGNC: 11572

OMIM: 187790

KEGG: hsa:6897

STRING: 9606.ENSP00000265112

UniGene: Hs.481860

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