TARS Antibody

Code CSB-PA023131ESR2HU
Size US$166
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  • Western blot
    All lanes: TARS antibody at 4.85µg/ml
    Lane 1: A549 whole cell lysate
    Lane 2: Hela whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 84, 87 kDa
    Observed band size: 84 kDa

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA023131ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA023131ESR2HU at dilution of 1:100

  • Immunoprecipitating TARS in A549 whole cell lysate
    Lane 1: Rabbit control IgG instead of CSB-PA023131ESR2HU in A549 whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
    Lane 2: CSB-PA023131ESR2HU (8µg) + A549 whole cell lysate (500µg)
    Lane 3: A549 whole cell lysate (10µg)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TARS Polyclonal antibody
Uniprot No.
Target Names
TARS
Alternative Names
cytoplasmic antibody; MGC9344 antibody; SYTC_HUMAN antibody; TARS antibody; Threonine tRNA ligase 1 antibody; Threonine tRNA ligase 1; cytoplasmic antibody; Threonine--tRNA ligase antibody; Threonyl tRNA synthetase antibody; Threonyl tRNA synthetase; cytoplasmic antibody; Threonyl-tRNA synthetase antibody; ThrRS antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Threonine--tRNA ligase, cytoplasmic protein (1-230AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC, IP
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
IP 1:200-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage.
Gene References into Functions
  1. Results show that TARS expression is increased in epithelial ovarian cancer. PMID: 25163878
  2. Our series mainly underscores that interstitial lung disease is frequent in anti-PL7(tars antibody)patients, leading to high morbidity. PMID: 23375620
  3. A previously undiscovered function for TARS as an angiogenic, pro-migratory extracellular signaling molecule. PMID: 23425968
Subcellular Location
Cytoplasm.
Protein Families
Class-II aminoacyl-tRNA synthetase family
Database Links

HGNC: 11572

OMIM: 187790

KEGG: hsa:6897

STRING: 9606.ENSP00000265112

UniGene: Hs.481860

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