TBC1D20 Antibody

Code CSB-PA846594LA01HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Western Blot
    Positive WB detected in: Mouse brain tissue, Mouse stomach tissue
    All lanes: TBC1D20 antibody at 4μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 46, 20, 49 kDa
    Observed band size: 46 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA846594LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA846594LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA846594LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Western Blot
    Positive WB detected in: A549 whole cell lysate, HepG2 whole cell lysate
    All lanes: TBC1D20 antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 46, 20, 49 kDa
    Observed band size: 46 kDa

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) TBC1D20 Polyclonal antibody
Uniprot No. Q96BZ9
Target Names TBC1D20
Alternative Names 1110028I04Rik antibody; 2810442O16Rik antibody; AI414693 antibody; C20orf140 antibody; FLJ45119 antibody; MGC94895 antibody; RP23 452D3.4 antibody; TBC1 domain family member 20 antibody; TBC1 domain family; member 20 antibody; Tbc1d20 antibody; TBC20_HUMAN antibody
Raised in Rabbit
Species Reactivity Human, Mouse
Immunogen Recombinant Human TBC1 domain family member 20 protein (1-237AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function GTPase-activating protein specific for Rab1 and Rab2 small GTPase families for which it can accelerate the intrinsic GTP hydrolysis rate by more than five orders of magnitude.
Gene References into Functions
  1. Warburg Micro syndrome is caused by TBC1D20 deficiency. PMID: 26063829
  2. Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans. PMID: 24239381
  3. The NS5A interaction with TBC1D20 and Rab1 is essential for the viral life cycle. PMID: 22491470
  4. These findings add TBC1D20 to the network of host factors regulating HIV replication cycle. PMID: 22260459
  5. TBC1D20 was found to be the first known GAP for Rab1, which is implicated in the regulation of anterograde traffic between the endoplasmic reticulum and the Golgi complex PMID: 17901050

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Involvement in disease Warburg micro syndrome 4 (WARBM4)
Subcellular Location Membrane, Multi-pass membrane protein
Database Links

HGNC: 16133

OMIM: 611663

KEGG: hsa:128637

STRING: 9606.ENSP00000346139

UniGene: Hs.590876

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