TMIGD2 Antibody

Code CSB-PA850263LA01HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
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  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA850263LA01HU at dilution of 1:100

  • Immunofluorescent analysis of PC-3 cells using CSB-PA850263LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) TMIGD2 Polyclonal antibody
Uniprot No. Q96BF3
Target Names TMIGD2
Alternative Names CD28H antibody; IGPR 1 antibody; IGPR1 antibody; immunoglobulin and proline-rich receptor 1 antibody; immunoglobulin-containing and proline-rich receptor 1 antibody; TMIG2_HUMAN antibody; TMIGD2 antibody; Transmembrane and immunoglobulin domain containing 2 antibody; Transmembrane and immunoglobulin domain-containing protein 2 antibody; transmembrane and immunoglobulin domain-containing protein 2 variant 2 antibody; transmembrane and immunoglobulin domain-containing protein 2 variant 3 antibody; UNQ3059/PRO9879 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Transmembrane and immunoglobulin domain-containing protein 2 protein (23-150AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
Gene References into Functions
  1. The authors demonstrate that IGPR-1 is localized to endothelial adherens junctions and, through trans-homophilic dimerization, regulates endothelial cell-cell adhesion and barrier function. PMID: 27838321
  2. B7 homologue 5 (B7-H5), was identified as a specific ligand for CD28H. PMID: 23784006
  3. Authors identified IGPR-1, also called TMIGD2, gene as a novel cell adhesion receptor that is expressed in various human organs and tissues, mainly in cells with epithelium and endothelium origins. PMID: 22419821
Subcellular Location Cell membrane, Single-pass type I membrane protein
Tissue Specificity Widely expressed, mainly by epithelial and endothelial cells, including bronchial epithelial cells of lung, breast glandular and lobular epithelia cells, urothelium of the bladder, skin epidermis, epithelium of gastrointestinal, rectum, endometrial glands
Database Links

HGNC: 28324

OMIM: 614715

KEGG: hsa:126259

UniGene: Hs.263928

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