TMIGD2 Antibody

Code CSB-PA850263LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA850263LA01HU at dilution of 1:100

  • Immunofluorescent analysis of PC-3 cells using CSB-PA850263LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TMIGD2 Polyclonal antibody
Uniprot No.
Target Names
TMIGD2
Alternative Names
CD28H antibody; IGPR 1 antibody; IGPR1 antibody; immunoglobulin and proline-rich receptor 1 antibody; immunoglobulin-containing and proline-rich receptor 1 antibody; TMIG2_HUMAN antibody; TMIGD2 antibody; Transmembrane and immunoglobulin domain containing 2 antibody; Transmembrane and immunoglobulin domain-containing protein 2 antibody; transmembrane and immunoglobulin domain-containing protein 2 variant 2 antibody; transmembrane and immunoglobulin domain-containing protein 2 variant 3 antibody; UNQ3059/PRO9879 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transmembrane and immunoglobulin domain-containing protein 2 protein (23-150AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TMIGD2 Antibody (Product code: CSB-PA850263LA01HU) is Non-conjugated. For TMIGD2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA850263LB01HU TMIGD2 Antibody, HRP conjugated ELISA
FITC CSB-PA850263LC01HU TMIGD2 Antibody, FITC conjugated
Biotin CSB-PA850263LD01HU TMIGD2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
Gene References into Functions
  1. The authors demonstrate that IGPR-1 is localized to endothelial adherens junctions and, through trans-homophilic dimerization, regulates endothelial cell-cell adhesion and barrier function. PMID: 27838321
  2. B7 homologue 5 (B7-H5), was identified as a specific ligand for CD28H. PMID: 23784006
  3. Authors identified IGPR-1, also called TMIGD2, gene as a novel cell adhesion receptor that is expressed in various human organs and tissues, mainly in cells with epithelium and endothelium origins. PMID: 22419821
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Widely expressed, mainly by epithelial and endothelial cells, including bronchial epithelial cells of lung, breast glandular and lobular epithelia cells, urothelium of the bladder, skin epidermis, epithelium of gastrointestinal, rectum, endometrial glands
Database Links

HGNC: 28324

OMIM: 614715

KEGG: hsa:126259

UniGene: Hs.263928

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