TMIGD2 Antibody, HRP conjugated

Datasheet

Code	CSB-PA850263LB01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TMIGD2 Polyclonal antibody

Uniprot No.

Q96BF3

Target Names

TMIGD2

Alternative Names

CD28H antibody; IGPR 1 antibody; IGPR1 antibody; immunoglobulin and proline-rich receptor 1 antibody; immunoglobulin-containing and proline-rich receptor 1 antibody; TMIG2_HUMAN antibody; TMIGD2 antibody; Transmembrane and immunoglobulin domain containing 2 antibody; Transmembrane and immunoglobulin domain-containing protein 2 antibody; transmembrane and immunoglobulin domain-containing protein 2 variant 2 antibody; transmembrane and immunoglobulin domain-containing protein 2 variant 3 antibody; UNQ3059/PRO9879 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Transmembrane and immunoglobulin domain-containing protein 2 protein (23-150AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.

Gene References into Functions

The authors demonstrate that IGPR-1 is localized to endothelial adherens junctions and, through trans-homophilic dimerization, regulates endothelial cell-cell adhesion and barrier function. PMID: 27838321
B7 homologue 5 (B7-H5), was identified as a specific ligand for CD28H. PMID: 23784006
Authors identified IGPR-1, also called TMIGD2, gene as a novel cell adhesion receptor that is expressed in various human organs and tissues, mainly in cells with epithelium and endothelium origins. PMID: 22419821

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Tissue Specificity

Widely expressed, mainly by epithelial and endothelial cells, including bronchial epithelial cells of lung, breast glandular and lobular epithelia cells, urothelium of the bladder, skin epidermis, epithelium of gastrointestinal, rectum, endometrial glands

Database Links

HGNC: 28324

OMIM: 614715

KEGG: hsa:126259

UniGene: Hs.263928

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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Target Therapy

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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