TRIM31 Antibody

Datasheet

Code	CSB-PA883650ESR2HU
Size	US$166
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Image	Western blot All lanes: TRIM31 antibody at 4.98 μg/ml Lane 1: HepG2 whole cell lysate Lane 2: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 49, 31 kDa Observed band size: 49, 70 kDa Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA883650ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA883650ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TRIM31 Polyclonal antibody

Uniprot No.

Q9BZY9

Target Names

TRIM31

Alternative Names

TRIM31 antibody; C6orf13 antibody; RNF antibody; E3 ubiquitin-protein ligase TRIM31 antibody; EC 2.3.2.27 antibody; RING-type E3 ubiquitin transferase TRIM31 antibody; Tripartite motif-containing protein 31 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human E3 ubiquitin-protein ligase TRIM31 protein (186-425AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Regulator of Src-induced anchorage independent cell growth. May have E3 ubiquitin-protein ligase activity.

Gene References into Functions

knockdown of TRIM31 reduced the expression of MMP2, MMP9 and phospho-Akt. PMID: 29864908
TRIM31 could promote hepatocellular carcinoma progression by targeting TSC1-TSC2 complex for degradation and further overactivating mTORC1 pathway. PMID: 28967907
feedback suppressor of NLRP3 inflammasome activity PMID: 27929086
Study reports that TRIM31 plays a critical role in the formation of autolysosomes in Atg5-/-or Atg7-/- cells, thus promoting elimination of invading bacteria through an Atg5- or Atg7-independent alternative pathway in the intestinal cells. PMID: 27216961
TRIM31 gene expression is regulated by miR-551b in ovarian cancer. PMID: 27743201
TRIM31 directly binds to NSE4, suggesting the existence of a TRIM31-MAGEA1-NSE4 complex reminiscent of the NSE1-NSE3-NSE4 trimer. PMID: 25590999
TRIM31 might serve as a tumor suppressor in non-small cell lung cancer. PMID: 24566900
The cellular level of TRIM31, an RBCC protein overexpressed in gastric cancer, is regulated by multiple mechanisms including the ubiquitin-proteasome system. PMID: 21231912
The TRIm31 gene is related to intelligence in an ADHD background. PMID: 21302343

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Subcellular Location

Cytoplasm. Mitochondrion. Note=Predominantly expressed in the cytoplasm but a fraction is associated with the mitochondria.

Protein Families

TRIM/RBCC family

Tissue Specificity

Up-regulated in gastric adenocarcinomas.

Database Links

HGNC: 16289

OMIM: 609316

KEGG: hsa:11074

STRING: 9606.ENSP00000365924

UniGene: Hs.493275

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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