UBE2G1 Antibody

Code CSB-PA025453GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
UBE2G1
Alternative Names
E217K antibody; UB2G1_HUMAN antibody; UBC 7 antibody; UBC7 antibody; UBC7 homolog yeast antibody; UBE 2G antibody; UBE2G antibody; Ube2g1 antibody; Ubiquitin carrier protein G1 antibody; Ubiquitin conjugating enzyme E2 G1 antibody; Ubiquitin conjugating enzyme E2G 1 (homologous to C. elegans UBC7) antibody; Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog C. elegans) antibody; Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog yeast) antibody; Ubiquitin conjugating enzyme E2G 1 antibody; Ubiquitin protein ligase G1 antibody; Ubiquitin-conjugating enzyme E2 G1 antibody; Ubiquitin-protein ligase G1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human UBE2G1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4.
Gene References into Functions
  1. ubiquitin binding by the acidic loops of Ube2g1 and Ube2r1 enzymes distinguishes their Lys-48-ubiquitylation activities PMID: 25471371
  2. study reports that UBCH8 and UBE2G1 and UBE2G2 cooperate with CRL4Cdt2 in promoting the polyubiquitylation and subsequent degradation of p21 and Cdt1, respectively PMID: 21628527
  3. In endoplasmic reticulum, involved in the degradation of type 2 iodothyronine selenodeiodinase PMID: 12933904
Protein Families
Ubiquitin-conjugating enzyme family
Tissue Specificity
Widely expressed, mainly in skeletal muscle.
Database Links

HGNC: 12482

OMIM: 601569

KEGG: hsa:7326

STRING: 9606.ENSP00000380178

UniGene: Hs.741319

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