UBE2J2 Antibody

Datasheet

Code	CSB-PA843143ESR2HU
Size	US$166
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Image	Western blot All lanes: Ubiquitin-conjugating enzyme E2 J2 antibody at 5μg/ml Lane 1: HepG2 whole cell lysate Lane 2: Rat small intestine tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 29, 25, 31 kDa Observed band size: 29 kDa Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA843143ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA843143ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA843143ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) UBE2J2 Polyclonal antibody

Uniprot No.

Q8N2K1

Target Names

UBE2J2

Alternative Names

NCUBE-2 antibody; NCUBE2 antibody; Non-canonical ubiquitin-conjugating enzyme 2 antibody; PRO2121 antibody; UB2J2_HUMAN antibody; UBC6 antibody; UBC6 homolog antibody; ube2j2 antibody; Ubiquitin conjugating enzyme 6 antibody; Ubiquitin-conjugating enzyme E2 J2 antibody; Yeast UBC6 homolog antibody

Raised in

Rabbit

Species Reactivity

Human, Rat

Immunogen

Recombinant Human Ubiquitin-conjugating enzyme E2 J2 protein (1-230AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD).

Gene References into Functions

UBE2G2 was crucial for the degradation of various immunoreceptors. UBE2J2, on the other hand, counteracted US2-induced endoplasmic reticulum-associated protein degradation by downregulating TRC8 expression. PMID: 28743740
Endoplasmic reticulum localization and cis-enzymatic activity play a role in regulating the steady state expression of human Ube2J2, ER localization and cis-enzymatic activity play a role in regulating the steady state expression of human Ube2J2. PMID: 25083800
analysis of involvement of E2 enzymes in specifying polyubiquitin chain assembly PMID: 20061386

Subcellular Location

Endoplasmic reticulum membrane; Single-pass type IV membrane protein.

Protein Families

Ubiquitin-conjugating enzyme family

Database Links

HGNC: 19268

KEGG: hsa:118424

UniGene: Hs.191987

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Protein processing in endoplasmic reticulum Ubiquitin mediated proteolysis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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