UBE2Z Antibody

Code CSB-PA025487GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
Alternative Names
FLJ13855 antibody; GC17P044341 antibody; HOYS7 antibody; Uba6 specific E2 conjugating enzyme 1 antibody; UBA6 specific enzyme E2 antibody; Uba6-specific E2 conjugating enzyme 1 antibody; UBE2Z antibody; UBE2Z_HUMAN antibody; Ubiquitin carrier protein Z antibody; Ubiquitin conjugating enzyme E2 Z antibody; Ubiquitin conjugating enzyme E2Z antibody; Ubiquitin protein ligase Z antibody; Ubiquitin-conjugating enzyme E2 Z antibody; Ubiquitin-protein ligase Z antibody; Use1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human UBE2Z
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the covalent attachment of ubiquitin to other proteins. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.
Gene References into Functions
  1. The SNP rs46522 in UBE2Z gene is associated with the risk of coronary Artery disease in the individuals of Chinese Han descent with type 2 diabetes and is of synergistic effect with Body mass index. PMID: 28840129
  2. we found that USE1 proteins were frequently overexpressed in human lung cancer. Furthermore, overexpression of USE1 promoted in vivo and in vitro proliferation, migration, and invasion. PMID: 28376205
  3. Association of UBE2Z single nucleotide polymorphism rs46522 with the susceptibility to coronary artery disease in an Iranian population. PMID: 26602883
  4. UBE2Z was widely expressed in human tissues and is located on chromosome 17q21. PMID: 17160626
  5. In tissue culture cells, Uba6 is required for charging a previously uncharacterized Uba6-specific E2 (Use1), whereas Ube1 is required for charging the cell-cycle E2s Cdc34A and Cdc34B PMID: 17597759

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Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Ubiquitin-conjugating enzyme family
Tissue Specificity
Widely expressed. Highly in placenta, pancreas, spleen and testis.
Database Links

HGNC: 25847

OMIM: 611362

KEGG: hsa:65264

STRING: 9606.ENSP00000354201

UniGene: Hs.514297

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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