UBE2Z Antibody

Datasheet

Code	CSB-PA875692ESR2HU
Size	US$166
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Image	Western blot All lanes: UBE2Z antibody at 3.37µg/ml Lane 1: MCF-7 whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: Hela whole cell lysate Lane 4: Mouse gonadal tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 39, 29 kDa Observed band size: 39 kDa Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA875692ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA875692ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) UBE2Z Polyclonal antibody

Uniprot No.

Q9H832

Target Names

UBE2Z

Alternative Names

FLJ13855 antibody; GC17P044341 antibody; HOYS7 antibody; Uba6 specific E2 conjugating enzyme 1 antibody; UBA6 specific enzyme E2 antibody; Uba6-specific E2 conjugating enzyme 1 antibody; UBE2Z antibody; UBE2Z_HUMAN antibody; Ubiquitin carrier protein Z antibody; Ubiquitin conjugating enzyme E2 Z antibody; Ubiquitin conjugating enzyme E2Z antibody; Ubiquitin protein ligase Z antibody; Ubiquitin-conjugating enzyme E2 Z antibody; Ubiquitin-protein ligase Z antibody; Use1 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Ubiquitin-conjugating enzyme E2 Z protein (115-354AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the covalent attachment of ubiquitin to other proteins. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.

Gene References into Functions

The SNP rs46522 in UBE2Z gene is associated with the risk of coronary Artery disease in the individuals of Chinese Han descent with type 2 diabetes and is of synergistic effect with Body mass index. PMID: 28840129
we found that USE1 proteins were frequently overexpressed in human lung cancer. Furthermore, overexpression of USE1 promoted in vivo and in vitro proliferation, migration, and invasion. PMID: 28376205
Association of UBE2Z single nucleotide polymorphism rs46522 with the susceptibility to coronary artery disease in an Iranian population. PMID: 26602883
UBE2Z was widely expressed in human tissues and is located on chromosome 17q21. PMID: 17160626
In tissue culture cells, Uba6 is required for charging a previously uncharacterized Uba6-specific E2 (Use1), whereas Ube1 is required for charging the cell-cycle E2s Cdc34A and Cdc34B PMID: 17597759

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Subcellular Location

Cytoplasm. Nucleus.

Protein Families

Ubiquitin-conjugating enzyme family

Tissue Specificity

Widely expressed. Highly in placenta, pancreas, spleen and testis.

Database Links

HGNC: 25847

OMIM: 611362

KEGG: hsa:65264

STRING: 9606.ENSP00000354201

UniGene: Hs.514297

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Ubiquitin mediated proteolysis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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