VDAC3 Antibody

Datasheet

Citations (1)

Code	CSB-PA162897
Size	US$166
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Image	Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA162897(VDAC3 Antibody) at dilution 1/400 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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Product Details
Citations
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9Y277

Target Names

VDAC3

Alternative Names

VDAC3 antibody; Voltage-dependent anion-selective channel protein 3 antibody; VDAC-3 antibody; hVDAC3 antibody; Outer mitochondrial membrane protein porin 3 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Full length fusion protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

Potentially Critical Roles of NDUFB5, TIMMDC1, and VDAC3 in the Progression of Septic Cardiomyopathy Through Integrated Bioinformatics Analysis Kang K, et al,Dna and Cell Biology,2019

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 1 reviews

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Applications : WB

Sample type: Mouse Heart tissue

Review: Expression of hub genes was measured by qRT- PCR and Western blotting. Scale bar: 20mm (A); mean–SEM value of at least six mice per group.

By Anonymous

Target Background

Function

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.

Gene References into Functions

The AG genotype of rs16891278 showed a significantly lower sperm concentration compared with the AA genotype (P = 0.044). Findings suggest that VDAC3 genetic variants may be associated with human sperm count. PMID: 28431403
This cohort study showed that the VDAC3 gene was down regulation between patients with idiopathic Parkinson disease and controls PMID: 28916538
VDAC3 is able to modulate its pore size and current by exploiting the mobility of the N-terminal and forming, upon external stimuli, disulfide bridges with cysteine residues located on the barrel and exposed to the inter-membrane space. PMID: 26806159
channel gating of VDAC3 might be controlled by redox sensing under physiological conditions PMID: 26407725
observed electrophysiological properties of hVDAC3 are surprisingly different from the other isoforms and are discussed in relation to the proposed physiological role of the protein in mammalian cells PMID: 25171321
a VDAC3-Mps1 module at the centrosome promotes ciliary disassembly during cell cycle entry. PMID: 23388454
VDAC3 is present at the mother centriole and modulates centriole assembly by recruiting Mps1 to centrosomes. PMID: 22935710
VDAC3 has a limited ability to support mitochondrial respiration and has no influence in the control of ROS production. PMID: 20138821
VDAC3 is a novel target for protein S-nigrosylation in spermatozoa. PMID: 17683036

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Subcellular Location

Mitochondrion outer membrane. Membrane.

Protein Families

Eukaryotic mitochondrial porin family

Tissue Specificity

Expressed in erythrocytes (at protein level). Widely expressed. Highest in testis.

Database Links

HGNC: 12674

OMIM: 610029

KEGG: hsa:7419

STRING: 9606.ENSP00000428845

UniGene: Hs.699301

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Calcium signaling pathway Cellular senescence Necroptosis NOD-like receptor signaling pathway cGMP-PKG signaling pathway Cholesterol metabolism

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