WNT8A Antibody, Biotin conjugated

Code CSB-PA863951LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) WNT8A Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
Protein Wnt-8a antibody; Protein Wnt-8d antibody; wingless type MMTV integration site family, member 8A antibody; WNT 8A antibody; Wnt 8d antibody; wnt8a antibody; WNT8A_HUMAN antibody; WNT8D antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein Wnt-8a protein (223-309AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in embryonic patterning.
Gene References into Functions
  1. Here, we show that Wnt/planar cell polarity (PCP) autocrine signaling controls the emergence of cytonemes, and that cytonemes subsequently control paracrine Wnt/beta-catenin signal activation. Upon binding of the Wnt family member Wnt8a, the receptor tyrosine kinase Ror2 becomes activated. PMID: 30060804
  2. the WNT8A gene is involved in the susceptibility to HSCR, and plays an important role in the occurrence and development of Hirschsprung's disease. PMID: 23836442
  3. Expression and regulation of WNT8A mRNA in human tumor cell lines PMID: 11956596
Subcellular Location
Secreted, extracellular space, extracellular matrix. Secreted.
Protein Families
Wnt family
Database Links

HGNC: 12788

OMIM: 606360

KEGG: hsa:7478

STRING: 9606.ENSP00000381739

UniGene: Hs.591274

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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