ZNF346 Antibody

Code CSB-PA026691ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA026691ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA026691ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA026691ESR1HU at dilution of 1:100

  • Immunoprecipitating ZNF346 in HepG2 whole cell lysate
    Lane 1: Rabbit control IgG (1µg) instead of CSB-PA026691ESR1HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG was used as the secondary antibody (1/50000)
    Lane 2: CSB-PA026691ESR1HU (4µg) + HepG2 whole cell lysate (500µg)
    Lane 3: HepG2 whole cell lysate (20µg)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZNF346 Polyclonal antibody
Uniprot No.
Target Names
ZNF346
Alternative Names
DKFZp547M223 antibody; Double stranded RNA binding zinc finger protein antibody; Double stranded RNA binding zinc finger protein JAZ antibody; JAZ antibody; Just another zinc finger protein antibody; Zfp346 antibody; Zinc finger protein 346 antibody; ZN346_HUMAN antibody; Znf346 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Zinc finger protein 346 protein (1-294AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC, IP
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IP 1:200-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity. May bind to specific miRNA hairpins.
Gene References into Functions
  1. JAZ directly binds E2F1 in vitro in a dsRNA-independent manner, and JAZ's dsRNA binding ZF domains, which are necessary for localizing JAZ to the nucleus, are required for repression of transcriptional activity in vivo. PMID: 21715977
  2. JAZ is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism PMID: 15254228
Subcellular Location
Nucleus, nucleolus. Cytoplasm. Note=Nuclear at steady state, primarily in the nucleolus. Shuttles between the nucleus and cytoplasm when associated with XPO5.
Database Links

HGNC: 16403

OMIM: 605308

KEGG: hsa:23567

STRING: 9606.ENSP00000350869

UniGene: Hs.484259

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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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