ZRANB1 Antibody, FITC conjugated

Code CSB-PA883378LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZRANB1 Polyclonal antibody
Uniprot No.
Target Names
ZRANB1
Alternative Names
DKFZp762P2216 antibody; hTrabid antibody; Trabid antibody; TRAF-binding protein domain antibody; Ubiquitin thioesterase ZRANB1 antibody; Zinc finger Ran-binding domain-containing protein 1 antibody; ZRAN1_HUMAN antibody; ZRANB1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ubiquitin thioesterase ZRANB1 protein (111-397AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.
Gene References into Functions
  1. Data show that the ankyrin-repeat ubiquitin-binding domain is crucial for TRABID efficiency and linkage specificity. PMID: 22157957
Subcellular Location
Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm.
Protein Families
Peptidase C64 family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 18224

OMIM: 611749

KEGG: hsa:54764

STRING: 9606.ENSP00000352676

UniGene: Hs.595158

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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