ZRANB1 Antibody, HRP conjugated

Code CSB-PA883378LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZRANB1 Polyclonal antibody
Uniprot No.
Target Names
ZRANB1
Alternative Names
DKFZp762P2216 antibody; hTrabid antibody; Trabid antibody; TRAF-binding protein domain antibody; Ubiquitin thioesterase ZRANB1 antibody; Zinc finger Ran-binding domain-containing protein 1 antibody; ZRAN1_HUMAN antibody; ZRANB1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ubiquitin thioesterase ZRANB1 protein (111-397AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.
Gene References into Functions
  1. Data show that the ankyrin-repeat ubiquitin-binding domain is crucial for TRABID efficiency and linkage specificity. PMID: 22157957
Subcellular Location
Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm.
Protein Families
Peptidase C64 family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 18224

OMIM: 611749

KEGG: hsa:54764

STRING: 9606.ENSP00000352676

UniGene: Hs.595158

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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