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kgp Antibody, FITC conjugated

Rare Species
Datasheet
Code CSB-PA464342LC01EXZ
Size US$166
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Product Details

Full Product Name
Rabbit anti-Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561) kgp Polyclonal antibody
Uniprot No.
B2RLK2
Target Names
kgp
Alternative Names
kgp antibody; PGN_1728Lys-gingipain antibody; EC 3.4.22.47 antibody; Lysine-specific cysteine proteinase Kgp) [Cleaved into: Lys-gingipain catalytic subunit; 39 kDa adhesin; 15 kDa adhesin; 44 kDa adhesin] antibody
Raised in
Rabbit
Species Reactivity
Porphyromonas gingivalis
Immunogen
Recombinant Porphyromonas gingivalis Lys-gingipain protein (229-594AA)
Immunogen Species
Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria.
Gene References into Functions
  1. a significant fraction of SPINK6-sensitive proteases in healthy saliva and confirmed the ability of gingipains to inactivate SPINK6 under ex vivo conditions PMID: 27354280
Subcellular Location
[Lys-gingipain catalytic subunit]: Secreted.
Protein Families
Peptidase C25 family
Database Links
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