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prn Antibody, FITC conjugated

Datasheet
Code CSB-PA321224LC01BUA
Size US$166
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Product Details

Full Product Name
Rabbit anti-Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) prn Polyclonal antibody
Uniprot No.
P14283
Target Names
prn
Alternative Names
prn antibody; omp69A antibody; BP1054 antibody; Pertactin autotransporter antibody; P.93) [Cleaved into: Outer membrane protein P.69; Pertactin translocator] antibody
Raised in
Rabbit
Species Reactivity
Bordetella pertussis
Immunogen
Recombinant Bordetella pertussis Pertactin autotransporter protein (632-910AA)
Immunogen Species
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Agglutinogen that binds to eukaryotic cells; a process mediated by the R-G-D sequence. Pertactin may have a role in bacterial adhesion, and thus play a role in virulence. May contribute to the disease state of whooping cough.
Gene References into Functions
  1. Prn-KO strains induced an increased production of pro-inflammatory cytokines by human and murine dendritic cell. PMID: 29559630
  2. Multiple driving forces required for efficient secretion of autotransporter virulence proteins, such as pertactin. PMID: 25670852
  3. Results indicate that the purified pertactin is a potential candidate as immunogen for preparation of diagnostic reagents and as a vaccine component. PMID: 20306653
Subcellular Location
[Pertactin autotransporter]: Periplasm.; [Outer membrane protein P.69]: Secreted. Cell surface.; [Pertactin translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Database Links

KEGG: bpe:BP1054

STRING: 257313.BP1054

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