Recombinant Human Eotaxin(CCL11)

Code CSB-EP004775HU
Product Type Recombinant Protein
Size US$1726
Uniprot No. P51671
Relevance In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias C-C motif chemokine 11 Eosinophil chemotactic protein Small-inducible cytokine A11
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence GPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP
Research Area Immunology
Source E.coli
Gene Names CCL11
Protein Names Recommended name: Eotaxin Alternative name(s): C-C motif chemokine 11 Eosinophil chemotactic protein Small-inducible cytokine A11
Expression Region 1-97aa
Tag Info N-terminal GST-tagged
Mol. Weight 35.4kDa
Protein Description Full Length
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
Subcellular Location Secreted
Protein Families Intercrine beta (chemokine CC) family
Database Links

HGNC: 10610

OMIM: 601156

KEGG: hsa:6356

STRING: 9606.ENSP00000302234

UniGene: Hs.54460

Pathway Chemokine signaling pathway
IL-17 signaling pathway

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