Product Details

Purity

Greater than 90% as determined by SDS-PAGE.

Target Names

IFNA6

Uniprot No.

P05013

Research Area

Cancer

Alternative Names

IFNA6Interferon alpha-6; IFN-alpha-6; Interferon alpha-54; Interferon alpha-K; LeIF K

Species

Homo sapiens (Human)

Source

E.coli

Expression Region

21-189aa

Target Protein Sequence

SLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFRFPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLEACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRNLQERLRRKE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Mol. Weight

25.1 kDa

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal 10xHis-tagged and C-terminal Myc-tagged

Form

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

3-7 business days

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet & COA

Please contact us to get it.

Description

The region for expressing recombinant Human IFNA6 contains amino acids 21-189. The expected molecular weight for the IFNA6 protein is calculated to be 25.1 kDa. This protein is generated in a e.coli-based system. The IFNA6 gene fragment has been modified by fusing the N-terminal 10xHis tag and C-terminal Myc tag, providing convenience in detecting and purifying the recombinant IFNA6 protein during the following stages.

Human interferon alpha-6 (IFNA6) belongs to the interferon alpha family, a group of cytokines crucial for the antiviral immune response. Produced by various immune cells, particularly leukocytes, IFNA6 plays a pivotal role in inhibiting viral replication and spread by inducing the expression of antiviral proteins within infected cells. Additionally, IFNA6 contributes to the activation of immune cells, enhancing the overall antiviral defense. Research on IFNA6 spans virology, immunology, and clinical medicine, exploring its potential therapeutic applications in treating viral infections, certain cancers, and autoimmune diseases. Understanding the molecular mechanisms of IFNA6 provides insights into the intricate interplay between the immune system and pathogens.

Target Background

Function

Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.

Subcellular Location

Secreted.

Protein Families

Alpha/beta interferon family

Database Links

HGNC: 5427

OMIM: 147566

KEGG: hsa:3443

STRING: 9606.ENSP00000369558

UniGene: Hs.533470

Code	CSB-EP011042HU
Abbreviation	Recombinant Human IFNA6 protein
MSDS	MSDS Datasheet
Size	$388
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Recombinant Human Interferon alpha-6 (IFNA6)

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