Recombinant Human Interleukin-10 receptor subunit beta(IL10RB),partial,Mammalian cell

Code CSB-MP600091HU
Product Type Recombinant Protein
Size Pls inquiry other sizes
Uniprot No. Q08334
Abbreviation IL10RB
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Purity >85% (SDS-PAGE)
Source Mammalian cell
Gene Names IL10RB
Protein Names Recommended name: Interleukin-10 receptor subunit beta Short name= IL-10 receptor subunit beta Short name= IL-10R subunit beta Short name= IL-10RB Alternative name(s): Cytokine receptor class-II member 4 Cytokine receptor
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Product Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Protein Description Partial
Target Details This protein belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.
HGNC 5965
RGD 1560373
MGI 109380
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Function Shared cell surface receptor required for the activation of five class 2 cytokines
Involvement in disease Inflammatory bowel disease 25 (IBD25)
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Type II cytokine receptor family
Database Links

HGNC: 5965

OMIM: 123889

KEGG: hsa:3588

STRING: 9606.ENSP00000290200

UniGene: Hs.654593

Pathway Jak-STAT signaling pathway

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