Purity
Greater than 85% as determined by SDS-PAGE.
Alternative Names
ATG8J; Autophagy-related protein LC3 C; Autophagy-related ubiquitin-like modifier LC3 C; LC3 like protein 2; MAP1 light chain 3 like protein 2; MAP1 light chain 3 like protein 3; MAP1 light chain 3-like protein 3; MAP1A/MAP1B LC3 C; MAP1A/MAP1B light chain 3 C; MAP1LC3C; Microtubule-associated protein 1 light chain 3 gamma; Microtubule-associated proteins 1A/1B light chain 3C; MLP3C_HUMAN
Species
Homo sapiens (Human)
Expression Region
1-126aa
Target Protein Sequence
MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLVPQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYASQETFG
Note: The complete sequence including tag
sequence, target protein sequence and linker sequence could be provided upon request.
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal 10xHis-tagged
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that
we have in stock, however, if you have any special requirement for the format, please remark your
requirement when placing the order, we will prepare according to your demand.
Buffer
Tris-based buffer，50% glycerol
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw
cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized
form is 12 months at -20°C/-80°C.
Lead Time
3-7 business days
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
Description
Amino acids 1-126 constitute the expression domain of recombinant Human MAP1LC3C. The calculated molecular weight for this MAP1LC3C protein is 20.7 kDa. The MAP1LC3C protein was expressed in e.coli. The N-terminal 10xHis tag was fused into the coding gene segment of MAP1LC3C, making it easier to detect and purify the MAP1LC3C recombinant protein in the later stages of expression and purification.
The human microtubule-associated protein 1A/1B light chain 3C (MAP1MAP1LC3C) is a member of the LC3 family and functions in the formation of autophagosomes, which are essential structures in autophagy, a cellular process responsible for degrading and recycling cellular components. MAP1LC3C undergoes lipidation, facilitating its association with autophagosomal membranes. Its involvement in autophagy allows for the targeted removal of damaged or obsolete cellular constituents. Research on MAP1LC3C focuses on understanding its precise role in autophagic processes, its regulation, and its implications in various physiological and pathological conditions, including neurodegenerative diseases and cancer.
