Recombinant Human Myosin light chain 3(MYL3)

Code CSB-EP015310HU
Size US$2466Purchase it in Cusabio online store
(only available for customers from the US)
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

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Product Details

Purity Greater than 90% as determined by SDS-PAGE.
Target Names MYL3
Uniprot No. P08590
Alternative Names Cardiac myosin light chain 1; CMH8 ; CMLC1; ELC of myosin; Essential light chain of myosin; MLC1SB; MLC1V; MYL3; MYL3_HUMAN; Myosin light chain 1; Myosin light chain 1 slow twitch muscle B/ventricular isoform; Myosin light chain 1 slow, B; Myosin light chain 3; Myosin, light chain 1, ventricular; myosin, light chain 3, alkali, ventricular, skeletal, slow; myosin, light polypeptide 3, alkali; myosin, light polypeptide 3, alkali, ventricular, skeletal, slow; OTTHUMP00000165922; Slow skeletal ventricular myosin alkali light chain 3; slow-twitch muscle B/ventricular isoform; Ventricular/slow twitch myosin alkali light chain; VLC1
Species Homo sapiens (Human)
Source E.coli
Expression Region 1-195aa
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Mol. Weight 48.8kDa
Protein Length Full Length
Tag Info N-terminal GST-tagged
Form Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA Please contact us to get it.

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Target Data

Function Regulatory light chain of myosin. Does not bind calcium.
Gene References into Functions
  1. In Familial Hypertrophic Cardiomyopathy, the MYL3 Arg94His variant was associated with high disease penetrance and substantial interventricular septal hypertrophy PMID: 26443374
  2. N-fragment is the binding domain of human ventricular LC1, whereas the C-fragment serves as a functional domain, which may be more involved in the modulation of the actin-activated ATPase activity of myosin PMID: 14516912
  3. Cell-permeable peptide containing the 15 amino acid N-terminal peptide from human ventricular light chain-1 (VLC-1) enhanced myocardial contractility. PMID: 17717642
Involvement in disease Cardiomyopathy, familial hypertrophic 8 (CMH8)
Database Links

HGNC: 7584

OMIM: 160790

KEGG: hsa:4634

STRING: 9606.ENSP00000292327

UniGene: Hs.517939


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