MYL3 Antibody

Code CSB-PA559001
Size US$297
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  • Western blot analysis of extracts from HuvEC, K562 and Jurkat cells, using MYL3 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MYL3 Polyclonal antibody
Uniprot No.
Target Names
MYL3
Alternative Names
Cardiac myosin light chain 1 antibody; CMH8 antibody; CMLC1 antibody; ELC of myosin antibody; Essential light chain of myosin antibody; MLC1SB antibody; MLC1V antibody; MYL3 antibody; MYL3_HUMAN antibody; Myosin light chain 1 antibody; Myosin light chain 1 slow twitch muscle B/ventricular isoform antibody; Myosin light chain 1 slow, B antibody; Myosin light chain 3 antibody; Myosin, light chain 1, ventricular antibody; myosin, light chain 3, alkali, ventricular, skeletal, slow antibody; myosin, light polypeptide 3, alkali antibody; myosin, light polypeptide 3, alkali, ventricular, skeletal, slow antibody; OTTHUMP00000165922 antibody; Slow skeletal ventricular myosin alkali light chain 3 antibody; slow-twitch muscle B/ventricular isoform antibody; Ventricular/slow twitch myosin alkali light chain antibody; VLC1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human MYL3.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulatory light chain of myosin. Does not bind calcium.
Gene References into Functions
  1. In Familial Hypertrophic Cardiomyopathy, the MYL3 Arg94His variant was associated with high disease penetrance and substantial interventricular septal hypertrophy PMID: 26443374
  2. N-fragment is the binding domain of human ventricular LC1, whereas the C-fragment serves as a functional domain, which may be more involved in the modulation of the actin-activated ATPase activity of myosin PMID: 14516912
  3. Cell-permeable peptide containing the 15 amino acid N-terminal peptide from human ventricular light chain-1 (VLC-1) enhanced myocardial contractility. PMID: 17717642
Involvement in disease
Cardiomyopathy, familial hypertrophic 8 (CMH8)
Database Links

HGNC: 7584

OMIM: 160790

KEGG: hsa:4634

STRING: 9606.ENSP00000292327

UniGene: Hs.517939

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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