Recombinant Human Paraneoplastic antigen Ma2 (PNMA2), partial

In Stock
Code CSB-EP018267HUa2
MSDS
Size US$306
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  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

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Product Details

Purity
Greater than 85% as determined by SDS-PAGE.
Target Names
PNMA2
Uniprot No.
Research Area
Tags & Cell Markers
Alternative Names
40 kDa neuronal protein; KIAA0883; MA2; MM2; Onconeuronal antigen Ma2; Paraneoplastic antigen Ma2; Paraneoplastic Ma antigen 2; Paraneoplastic neuronal antigen ; Paraneoplastic neuronal antigen MM2; PNMA2; PNMA2_HUMAN; Retrotransposon gag domain containing 2; RGAG2
Species
Homo sapiens (Human)
Source
E.coli
Expression Region
2-361aa
Target Protein Sequence
ALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQEVLQETLKSLGRYRLLGKIFRKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGMFRALGQEGVSPATVPCISPELLAHLLGQAMAHAPQPLLPMRYRKLRVFSGSAVPAPEEESFEVWLEQATEIVKEWPVTEAEKKRWLAESLRGPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRRIADQVRLEQVMAGATLNQMLWCRLRELKDQGPPPSFLELMKVIREEEEEEASFENESIEEPEERDGYGRWNHE
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Mol. Weight
57.1 kDa
Protein Length
Partial
Tag Info
N-terminal 6xHis-SUMO-tagged
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
3-7 business days
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Gene References into Functions
  1. PNMA2 functions as antagonist of MOAP-1 and PNMA1 through heterodimeric interaction PMID: 27003254
  2. Immunohistochemical analysis of MA2/D2-40 combined with p16(INK4A) may have a significant implication in clinical practice for better identifying the grade of cervical intraepithelial neoplasia. PMID: 21729305
  3. Ma2 may have a role in early recurrence of small intestine neuroendocrine tumors PMID: 21209860
Subcellular Location
Nucleus, nucleolus.
Protein Families
PNMA family
Tissue Specificity
Brain-specific. In some cancer patients, specifically expressed by testicular tumor cells.
Database Links

HGNC: 9159

OMIM: 603970

KEGG: hsa:10687

STRING: 9606.ENSP00000429344

UniGene: Hs.591838

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