Code | CSB-EP026136HU |
MSDS | |
Size | US$256 |
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The recombinant Human WNT3A was expressed with the amino acid range of 19-352. The calculated molecular weight for this WNT3A protein is 43.5 kDa. The WNT3A protein was expressed in e.coli. The N-terminal 10xHis tag was smoothly integrated into the coding gene of WNT3A, which enables a simple process of detecting and purifying the WNT3A recombinant protein in the following steps.
The human protein Wnt-3a (WNT3A) is a member of the Wnt signaling pathway, which is crucial for embryonic development, tissue homeostasis, and various physiological processes. WNT3A is a secreted glycoprotein that acts as a ligand for cell surface receptors, initiating signaling cascades that regulate gene expression. In embryonic development, WNT3A plays a pivotal role in axis formation and organogenesis. Additionally, it is involved in tissue regeneration, stem cell maintenance, and adult tissue homeostasis. Dysregulation of WNT3A signaling has been implicated in various diseases, including cancer, where aberrant activation can contribute to tumor initiation and progression. Understanding the functions and regulatory mechanisms of WNT3A provides valuable insights into both developmental processes and the molecular basis of diseases. Research on WNT3A spans diverse fields, including developmental biology, regenerative medicine, and cancer biology, making it a significant target for therapeutic interventions.There are currently no reviews for this product.