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| Code | CSB-YP004931HU |
| Product Type | Recombinant Protein |
| Size | US$2010 |
| Uniprot No. | P07766 |
| Lead Time | 3-7 business days |
| Relevance | The CD3 complex mediates signal transduction, resulting in T-cell activation and proliferation. Required for normal immune responses (PubMed:15546002, PubMed:8490660). |
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| Storage Buffer | Tris-based buffer,50% glycerol |
| Alias | T-cell surface antigen T3/Leu-4 epsilon chain;CD_antigen: CD3e |
| Species | Homo sapiens (Human) |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Research Area | Immunology |
| Source | Yeast |
| Gene Names | CD3E |
| Protein Names | Recommended name: T-cell surface glycoprotein CD3 epsilon chainAlternative name(s): T-cell surface antigen T3/Leu-4 epsilon chain CD_antigen= CD3e |
| Tag Info | The following tags are available. N-terminal His-tagged Tag-Free |
| Mol. Weight | 13.8kDa |
| Protein Description | Partial |
| Storage | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
| Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways |
| Involvement in disease | Immunodeficiency 18 (IMD18) |
| Subcellular Location | Cell membrane, Single-pass type I membrane protein |
| Database Links |
HGNC: 1674 OMIM: 186830 KEGG: hsa:916 STRING: 9606.ENSP00000354566 UniGene: Hs.3003 |
| Pathway |
Hematopoietic cell lineage
T cell receptor signaling pathway Th1 and Th2 cell differentiation Th17 cell differentiation |
CD3E Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA10484A0Rb | CD3E Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA10484C0Rb | CD3E Antibody, FITC conjugated | Human | ELISA |
| CSB-PA10484D0Rb | CD3E Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA10484B0Rb | CD3E Antibody, HRP conjugated | Human | ELISA |
| CSB-PA004931HA01HU | CD3E Antibody | Human | ELISA, IHC, IF |
CD3E Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA004931GA01HU | CD3E Antibody | Human | ELISA,WB,IHC |
| CSB-PA949010 | CD3E Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA005833 | CD3E Antibody | Human | WB,ELISA |
| CSB-PA070244 | CD3E Antibody | Human | WB,IHC,ELISA |
| CSB-PA004931HB01HU | CD3E Antibody, HRP conjugated | Human | ELISA |
| CSB-PA004931HC01HU | CD3E Antibody, FITC conjugated | Human | ELISA |
| CSB-PA004931HD01HU | CD3E Antibody, Biotin conjugated | Human | ELISA |
CD3E Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-EP004931HU | Recombinant Human T-cell surface glycoprotein CD3 epsilon chain(CD3E),partial | E.coli |
| CSB-CF004931HU | Recombinant Human T-cell surface glycoprotein CD3 epsilon chain(CD3E) | in vitro E.coli expression system |
| CSB-EP004931HU(A4) | Recombinant Human T-cell surface glycoprotein CD3 epsilon chain(CD3E) | E.coli |
| CSB-BP004931HU CSB-MP004931HU |
Recombinant Human T-cell surface glycoprotein CD3 epsilon chain(CD3E),partial | Baculovirus Mammalian cell |
CD3E ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL004931HU | Human T-cell surface glycoprotein CD3 epsilon chain(CD3E) ELISA kit | Request Information |
Recombinant Chicken Collagen alpha-1(XII) chain(COL12A1) ,partial
Express system: E.coli
Species: Gallus gallus (Chicken)
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Recombinant Human Bone sialoprotein 2 (IBSP),Partial
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Horse Serum amyloid A protein(SAA1)
Express system: E.coli
Species: Equus caballus (Horse)
Recombinant Human Diacylglycerol kinase gamma(DGKG),partial
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Receptor-type tyrosine-protein phosphatase C(PTPRC),partial
Express system: Yeast
Species: Homo sapiens (Human)
Recombinant Human Integrin alpha-IIb(ITGA2B),partial
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Apolipoprotein B-100(APOB),partial
Express system: Yeast
Species: Homo sapiens (Human)
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