Endotoxin

Less than 1.0 EU/ug as determined by LAL method.

Activity

Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus LTBR at 2 μg/ml can bind human TNFSF14 (CSB-MP023991HUj7-B), the EC50 is 11.83-14.23 ng/ml.

Target Names

LTBR

Uniprot No.

A0A2K5VGQ6

Alternative Names

/

Species

Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Source

Mammalian cell

Expression Region

28-229aa

Target Protein Sequence

SQPQVVRKGPVPPYGSENQTCRDQEKEYYEPRHRICCSRCPPGTYVSAKCSRSRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCEDQGLVEAAPGTAQSDTTCRNPSESLPPEMSGT

Mol. Weight

23.6kDa

Protein Length

Partial

Tag Info

C-terminal 10xHis-tagged

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer

Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

3-7 business days

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet & COA

Please contact us to get it.

Description

Lymphotoxin beta receptor mediates critical signals in lymphoid organogenesis and immune homeostasis, making its extracellular domain a key target for dissecting TNFSF14/LIGHT interactions in primate models. This cynomolgus macaque LTBR fragment spanning residues 28–229 demonstrates quantifiable binding to human TNFSF14 with an EC50 of 11.83–14.23 ng/ml in functional ELISA, providing a validated reagent for ligand-binding assays, competitive inhibition studies, and blocking antibody screening in translational research. Mammalian cell expression preserves the native glycosylation and disulfide architecture essential for physiological receptor conformation, supporting its use in therapeutic antibody epitope mapping, SPR-based affinity characterization, and small-molecule inhibitor screening campaigns. The protein meets the purity and endotoxin criteria typical for quantitative binding assays, with >95% purity by SDS-PAGE and <1.0 EU/μg endotoxin, aligning with standards expected in drug discovery workflows targeting the lymphotoxin pathway.

Code	CSB-MP6176MOV
Abbreviation	Recombinant Cynomolgus monkey LTBR protein, partial (Active)
MSDS	MSDS Datasheet
Size	$138
	Order now
Image	(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel. Activity Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus LTBR at 2 μg/ml can bind human TNFSF14 (CSB-MP023991HUj7-B), the EC₅₀ is 11.83-14.23 ng/ml. Biological Activity Assay
Have Questions?	Leave a Message or Start an on-line Chat

Recombinant Macaca fascicularis Lymphotoxin beta receptor (LTBR), partial (Active)

Product Details

Related Products

Customer Reviews and Q&A

×CloseMessage