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Recombinant Macaca fascicularis Seizure related 6 homolog (SEZ6), partial (Active)

Recombinant Macaca fascicularis Seizure related 6 homolog (SEZ6), partial (Active)

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Code	CSB-MP6419MOV
Abbreviation	Recombinant Cynomolgus monkey SEZ6 protein, partial (Active)
MSDS	MSDS Datasheet
Size	$190
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Image	(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel. Activity Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis SEZ6 at 2 μg/ml can bind Anti-SEZ6 recombinant antibody (CSB-RA684467MA1HU). The EC₅₀ is 0.6865-1.065 ng/mL. Biological Activity Assay
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Product Details
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Product Details

Purity

≥ 95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU/ug as determined by LAL method.

Activity

Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis SEZ6 at 2 μg/mL can bind Anti-SEZ6 recombinant antibody (CSB-RA684467MA1HU). The EC50 is 0.6865-1.065 ng/mL.

Target Names

SEZ6

Uniprot No.

A0A2K5WPJ4

Alternative Names

Seizure related 6 homolog; SEZ6

Species

Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Source

Mammalian cell

Expression Region

20-927aa

Target Protein Sequence

LSSEAPTMGKGQAPGIEETDGELTAAPTPEQPERGVHFVTTAPTLKLLNHHPLLEEFLQEGLEKGDEELRPALPFQPDPPTPFTPSPLPRLANQDSRPVFTSPTPATAAVPTQPQSKEGPWSLESEPPVLRITAPLPPGPSMAVPTLRPGERPSTTPPSRAWTPTQEGPGDMGRPWVPEVVSQGAGIGIQGTIASSTASGDDEETTTTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSSPPDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPHRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSAPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDVRVLRIGPGDVLTFYDGDDLTARVLGQYSGPHSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPDLVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLTGTSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKRLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICKAASLDGFYNSRSLDVAKAPAASSTLDAAH

Mol. Weight

99.3 kDa

Protein Length

Partial

Tag Info

C-terminal 10xHis-tagged

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer

Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

3-7 business days

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet & COA

Please contact us to get it.

Description

SEZ6 plays a critical role in neuronal development and synapse formation, making it a valuable target for investigating neurodevelopmental disorders and epilepsy mechanisms. This cynomolgus monkey ortholog, spanning residues 20–927, demonstrates robust antibody-binding activity with an EC50 of 0.69–1.07 ng/mL in functional ELISA, providing quantitative evidence that supports its use in antibody development workflows, epitope mapping studies, and immunoassay standardization. Mammalian cell expression preserves the native post-translational modifications characteristic of primate SEZ6, which is essential for maintaining physiologically relevant protein conformation in binding experiments. The protein meets quality thresholds commonly required for cell-based assays and in vivo studies, with purity exceeding 95% by SDS-PAGE and endotoxin levels below 1.0 EU/μg.