Recombinant Macaca fascicularis tumor-associated calcium signal transducer 2 (TACSTD2), partial (Active)

TACSTD2 plays a critical role in epithelial cell adhesion and has emerged as a therapeutic target in multiple carcinomas, making functional protein reagents essential for antibody development and mechanistic studies. This recombinant cynomolgus macaque TACSTD2 (aa 31–274) demonstrates specific antibody binding in functional ELISA with an EC50 of 2.103–2.767 ng/mL, confirming proper epitope presentation that supports antibody validation workflows and epitope mapping experiments. The yeast expression system yields protein exceeding 90% purity as determined by SDS-PAGE, with endotoxin levels below 1.0 EU/μg—criteria that align with standards expected in cell-based assays including adhesion studies and migration experiments where low endotoxin is critical for preserving cell viability and behavior. Researchers investigating tumor metastasis mechanisms or developing therapeutic antibodies against TACSTD2 can utilize this reagent for binding assays and functional characterization in a non-human primate model relevant to translational oncology research.