Recombinant Mouse Proto-oncogene Wnt-3(Wnt3)

Code CSB-YP026135MO
Product Type Recombinant Protein
Size US$2474
Uniprot No. P17553
Relevance Ligand for mbers of the frizzled family of seven transmbrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias Proto-oncogene Int-4
Species Mus musculus (Mouse)
Purity Greater than 90% as determined by SDS-PAGE.
Research Area Others
Source Yeast
Gene Names Wnt3
Protein Names Recommended name: Proto-oncogene Wnt-3 Alternative name(s): Proto-oncogene Int-4
Expression Region 22–355aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 36.9kDa
Protein Description Full Length of Mature Protein
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
Subcellular Location Secreted, extracellular space, extracellular matrix
Protein Families Wnt family
Tissue Specificity Detected at low levels in adult brain (PubMed:2162045). Dorsal portion of the neural tube, dorsal ectoderm, the branchial arches, and the limb buds.
Database Links

KEGG: mmu:22415

STRING: 10090.ENSMUSP00000000127

UniGene: Mm.159091

Pathway Hippo signaling pathway
mTOR signaling pathway
Wnt signaling pathway
Signaling pathways regulating pluripotency of stem cells

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