Code | CSB-RA213635A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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WB | 1:500-1:5000 |
The production process for the ACTR3 recombinant monoclonal antibody consists of four key steps: firstly, sequencing the ACTR3 monoclonal antibody gene; secondly, cloning the gene into a plasmid vector; thirdly, introducing the recombinant vector into a host cell line; fourthly, purifying the ACTR3 recombinant monoclonal antibody from the cell culture supernatant by using affinity chromatography. The ACTR3 monoclonal antibody is developed from hybridomas that produce the ACTR3 antibody. During the production of the ACTR3 monoclonal antibody, a synthesized peptide derived from the human ACTR3 is utilized as the immunogen. The ACTR3 recombinant monoclonal antibody is recommended for use in detecting human ACTR3 protein in ELISA and WB applications.
The ACTR3 protein is a member of the actin family of proteins and plays an important role in the assembly and organization of actin filaments in cells. Specifically, it is a component of the Arp2/3 complex, which is a critical regulator of actin polymerization and cytoskeleton dynamics. The Arp2/3 complex promotes the nucleation of new actin filaments from existing filaments, leading to the formation of branched actin networks that are important for many cellular processes, including cell motility, endocytosis, and cell division. ACTR3 is thought to be particularly important in the regulation of cell motility, and studies have suggested that it may be involved in the formation of filopodia and lamellipodia, which are dynamic actin-rich protrusions that facilitate cell movement.
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