Code | CSB-RA062241A0HU |
Size | US$210 |
Order now | |
Image |
|
Have Questions? | Leave a Message or Start an on-line Chat |
Application | Recommended Dilution |
---|---|
FC | 1:50-1:200 |
The BECN1 recombinant monoclonal antibody is created through the utilization of in vitro expression systems. These systems are established by cloning the DNA sequences of BECN1 antibodies obtained from immunoreactive rabbits. The immunogen employed in this process is a synthesized peptide derived from the human BECN1 protein. Subsequently, the genes encoding the BECN1 antibodies are inserted into plasmid vectors, and these recombinant plasmid vectors are then transfected into host cells to enable the expression of the antibody. Following expression, the BECN1 recombinant monoclonal antibody undergoes affinity-chromatography purification. Rigorous testing in ELISA and FC applications confirms its reactivity with the human BECN1 protein.
BECN1 is a key component of the autophagic machinery and is essential for the initiation and regulation of autophagy, a process that plays a central role in cellular quality control, homeostasis, and responses to stress. Dysregulation of BECN1 and autophagy has been implicated in various diseases, including cancer, neurodegenerative disorders, and infectious diseases.
There are currently no reviews for this product.