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Beclin-1 is a protein in humans that is encoded by BECN1 gene. Plays a central role in autophagy.
The following BECN1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
BECN1 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA002658GA01HU | BECN1 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA055976 | BECN1 Antibody |
Human | ELISA,WB |
| CSB-PA080157 | BECN1 Antibody |
Human,Mouse,Rat | WB |
| CSB-PA080252 | BECN1 Antibody |
Human | WB |
| CSB-PA554462 | BECN1 Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA663809 | BECN1 Antibody |
Human,Mouse | WB,ELISA |
| CSB-MA365521 | BECN1 Monoclonal Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-MA110682 | BECN1 Monoclonal Antibody |
Human,Mouse,Rat | ELISA,IHC |
| CSB-MA991880 | BECN1 Monoclonal Antibody |
Human,Mouse,Rat | ELISA,IHC |
| CSB-PA617917LA01HU | BECN1 Antibody |
Human, Mouse | ELISA, WB, IHC, IF |
| CSB-PA617917LB01HU | BECN1 Antibody, HRP conjugated |
Human | ELISA |
BECN1 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA198001XA01DIL | becn1 Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
BECN1 Antibodies for Mus musculus (Mouse)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA002658ZA01MO | Becn1 Antibody |
Mus musculus | ELISA, WB (ensure identification of antigen) |
BECN1 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP002658MO CSB-BP002658MO CSB-MP002658MO CSB-EP002658MO-B |
Recombinant Mouse Beclin-1(Becn1) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP002658MO | Recombinant Mouse Beclin-1(Becn1) |
E.coli |
BECN1 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP617917HU CSB-BP617917HU CSB-MP617917HU CSB-EP617917HU-B |
Recombinant Human Beclin-1(BECN1) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BECN1 Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP671073BO CSB-EP671073BO CSB-BP671073BO CSB-MP671073BO CSB-EP671073BO-B |
Recombinant Bovine Beclin-1(BECN1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BECN1 Proteins for Sus scrofa (Pig)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP672191PI CSB-EP672191PI CSB-BP672191PI CSB-MP672191PI CSB-EP672191PI-B |
Recombinant Pig Beclin-1(BECN1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BECN1 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP673319XBF CSB-EP673319XBF CSB-BP673319XBF CSB-MP673319XBF CSB-EP673319XBF-B |
Recombinant Xenopus tropicalis Beclin-1(becn1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BECN1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP728963PYX CSB-EP728963PYX CSB-BP728963PYX CSB-MP728963PYX CSB-EP728963PYX-B |
Recombinant Pongo abelii Beclin-1(BECN1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BECN1 Proteins for Gallus gallus (Chicken)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP733554CH CSB-EP733554CH CSB-BP733554CH CSB-MP733554CH CSB-EP733554CH-B |
Recombinant Chicken Beclin-1(BECN1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BECN1 Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP756964XBE CSB-EP756964XBE CSB-BP756964XBE CSB-MP756964XBE CSB-EP756964XBE-B |
Recombinant Xenopus laevis Beclin-1(becn1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BECN1 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP849672RA CSB-EP849672RA CSB-BP849672RA CSB-MP849672RA CSB-EP849672RA-B |
Recombinant Rat Beclin-1(Becn1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BECN1 ELISA Kit for Rattus norvegicus (Rat)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL002658RA | Rat Beclin-1(BECN1) ELISA kit |
serum, plasma, tissue homogenates | 0.039 ng/mL |
Beclin-1 is a protein in humans that is encoded by the BECN1 gene. The BECN1 protein is a mammalian ortholog of the yeast autophagy-related gene 6 (Atg6) and BEC-1 in the C. elegans nematode. This protein interacts with either BCL-2 or PI3k class III, playing a critical role in the regulation of both autophagy and cell death. BECN1 also plays a central role in autophagy. In addition to its role in autophagy, BECN1 is an important player in tumorigenesis, and neurodegeneration, being implicated in the autophagic programmed cell death. Ovarian cancer with upregulated autophagy has a less aggressive behavior and is more responsive to chemotherapy. Schizophrenia is associated with low levels of BECN1 in the hippocampus of the affected which causes diminished autophagy which in turn results in increased neuronal cell death.
