Code | CSB-RA783071A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
The CR1 recombinant monoclonal antibody generation involves the retrieval of CR1 antibody genes from B cells sourced from immunoreactive rabbits, followed by their amplification and cloning into appropriate phage vectors. These vectors are then introduced into mammalian cell lines, enabling the production of functional antibodies. Subsequently, the CR1 recombinant monoclonal antibody is isolated from the culture supernatant of the transfected cell lines and is purified through affinity chromatography. After rigorous verification, the antibody can be used in ELISA and IHC applications, facilitating the precise detection of human CR1 protein.
Complement Receptor type 1 (CR1) is a multifunctional receptor that plays a central role in regulating the complement system. Its functions include complement cascade regulation, opsonization, immune complex clearance, immune tolerance, and the protection of host cells from complement-mediated damage. It is a critical component of both the innate and adaptive immune responses.
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