Code | CSB-RA188594A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
GPX4 is a selenoprotein glutathione peroxidase that reduces highly hazardous lipid hydroperoxides in membranes to less toxic lipid alcohols using glutathione as an electron donor. GPX4 is a leading inhibitor of ferroptosis due to its unique function to reduce complex hydroperoxides including phospholipid hydroperoxides and cholesterol hydroperoxides to their corresponding counterparts, thereby blocking the lipid peroxidation chain reaction. Studies have shown that GPX4 is a necessary enzyme for motor neuron health and survival.
Genes for GPX4 antibody's heavy and light chains were cloned into plasma vectors, which were subsequently transfected into mammalian cells for expression. The resulting product is the recombinant GPX4 antibody. This recombinant GPX4 antibody was subsequently purified from the culture medium of transfected host cell lines through A synthesized peptide derived from human GPX4. It has verified to detect GPX4 protein Human in the ELISA, IHC.There are currently no reviews for this product.