Code | CSB-RA904344A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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FC | 1:50-1:200 |
Immunizing the rabbit with the synthesized peptide derived from human GRIN1 protein and then isolating B cells from the immunized rabbit, followed by extracting RNA from the B cells. The extracted RNA was reversely transcribed into cDNA, which acted as the template to extend GRIN1 antibody genes with degenerate primer. The synthesized GRIN1 antibody genes were inserted into the plasmid vector and then transfected into host cells for expression. The GRIN1 recombinant monoclonal antibody was purified from the cell culture supernatant through affinity chromatography. It was subjected to ELISA and FC applications. It can react with human GRIN1 protein.
The GRIN1 protein, as a subunit of the NMDA receptor, is central to various essential processes in the nervous system, including synaptic plasticity, learning, memory, and normal neurotransmission. Dysregulation of NMDA receptors can have significant implications for neurological health and disorders.
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