Code | CSB-RA593846A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
IHC | 1:50-1:200 |
HDAC2, a member of the class I HDAC family, can deacetylate the N-terminal of histone H3 and H4, resulting in a more compacted chromatin structure and transcriptional gene silencing. It plays a role in the onset and development of renal, cardiovascular, neurological, and lung disease. HDAC2 regulates gene transcription, chromatin remodeling, signal transduction, and nuclear reprogramming, making it a potential therapeutic target for liver disease. Inhibitors of HDAC2, such as small molecular compounds, peptides, and other biological agents, have shown promise in the therapy of cancer, as well as degenerative and inflammatory immunological diseases.
Compared with the polyclonal and monoclonal antibodies of HDAC2, this HDAC2 recombinant antibody has the features of increased reproducibility and control, animal-free technology, high degree of monovalency, high batch-to-batch consistency, easier isotype conversion, etc. And it has been validated in ELISA, WB, IHC.There are currently no reviews for this product.