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Human IgG1&Igκ Isotype Recombinant Monoclonal Antibody

Human IgG1&Igκ Isotype Recombinant Monoclonal Antibody

Datasheet

Code	CSB-RA011156MA1HU
Size	US$210
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Image	Untransfected MC38 cells and transfected Human TSPAN8 MC38 stable cells were stained with Human IgG1&Igκ Isotype Control (CSB-RA011156MA1HU) and anti-TSPAN8 antibody (CSB-RA025166MA1HU) (2µg/110⁶cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. HT29 cells were stained with Human IgG1&Igκ Isotype Control (CSB-RA011156MA1HU)(green line) and anti-TSPAN8 antibody (CSB-RA882142MA1HU) (2µg/110⁶cells) (red line), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. The purity of Human IgG1&Igκ Isotype was greater than 95% as determined by SEC-HPLC
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Product Details
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Target Background

Product Details

Uniprot No.

P01857

Target Names

IgG1

Alternative Names

Human IgG1

Species Reactivity

Human

Immunogen

Recombinant Human IgG1 protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Monoclonal

Isotype

hIgG1

Clone No.

4D2

Purification Method

Affinity-chromatography

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

Recommended Dilution

Application	Recommended Dilution
FC	1:50-1:200

Protocols

Flow Cytometry (FC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.

Involvement in disease

Multiple myeloma (MM)

Subcellular Location

Secreted. Cell membrane.

Database Links

HGNC: 5525

OMIM: 147100

UniGene: Hs.510635

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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